where tumors or cancer cells need to be removed from the body through a surgical procedure. In this Thesis the nature of factors released in culture supernatants (SNs) by alloantigen and mitogen stimulation of Xenopus leucocytes is re examined and it is shown that cells other than T lymphoblasts and even non T cells are responsive to such T cell derived 'lymphokines'. Chapter 2 revealed that SNs collected from 48 hour cocultures of splenocytes from MHC (major histocompatibility complex) disparate Xenopus were able to achieve enhanced proliferation not only of PHA activated splenic lymphoid cells
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